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At the high end (10 units): 1.0 mg of combined peptide, which is 0.5 mg of TB-500 per injection

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Together, by evaluating the role of each transport model onto a benchmark CNS dataset, our data suggest that the BBB model most accurately predicts the CNS benchmark data and that all models together correctly predict compounds as non-CNS penetrant based on a large MW, hydrophilicity, proton donors and acceptors, as well as a high TPSA